1/10/2024 0 Comments Chinese style arial font![]() ![]() Finally, the binding ability of the active ingredient and the key target was verified by molecular docking. ![]() Cytoscape software was used to build the topological network diagram of the drug-compound-target path. The cross targets were imported into the Metascape database for Gene Oncology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. Myocardial ischemia were then selected, and the protein-protein interaction (PPI) network was constructed based on the STRING database. Genecards database was used to obtain targets related to myocardial ischemia. Firstly, based on the traditional Chinese medicine systems pharmacology (TCMSP), the related compounds of SM and CT were obtained, and the potential targets of these compounds were collected by the target fishing method. Abstract: Based on network pharmacology and molecular docking technology, the similarities and differences of anti-myocardial ischemia mechanism between Salvia miltiorrhiza Bunge (SM) and Carthamus tinctorius L.
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